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Ten years of hope and heartbreak for the Mc. Canns. To the unenlightened eye, the scene at the Luz Ocean Club in Portugal’s Algarve this week was nothing short of picture perfect. Beneath the brilliant sunshine and under the watchful gaze of their parents, children frolicked in the turquoise waters of the hotel’s three swimming pools.

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Families meandered through the sub- tropical gardens and along the tree- lined promenade to watch the white- tipped waves from the Atlantic rolling into the sandy bay. Certainly there was nothing tangible to remind hotel guests of the terrible events that occurred here exactly ten years ago. Pictured: Madeleine's Mc.

Cann's parents Kate and Gerry at a press conference. Yesterday, detectives said a ‘significant line of inquiry’ had been opened into her disappearance. Pictured: Madeleine as a three- year- old, left, and,  right, what police said she could have looked like as a nine- year- old. The disappearance of three- year- old Madeleine Mc. Cann from her family’s rented two- bedroom holiday apartment at the Ocean Club sparked one of the most baffling mysteries of modern times.

The disappearance of three- year- old Madeleine Mc. Cann from her family’s rented two- bedroom holiday apartment at the Ocean Club sparked one of the most baffling mysteries of modern times. Yesterday, detectives said a ‘significant line of inquiry’ is the final throw of the dice which could end a decade of heartbreak for her family, and have returned to the theory burglars are linked to her disappearance. For her parents Kate and Gerry, this has become their new ‘normal’. Scraps of hope proffered and then snatched away over the past ten years. Back in the Mc. Canns’ home village of Rothley, Leicestershire, green and yellow ribbons, symbolising hope and solidarity, are permanently tied to the gates of the family house.

Inside, Madeleine’s untouched bedroom is piled high with a decade’s worth of unopened birthday and Christmas presents — a symbol of the couple’s unwavering conviction their eldest daughter could come home one day. They have coped in different ways with the tragedy. Back then, they were professional doctors: he a consultant cardiologist, she a family GP. Today, Kate, 4. 9, still hasn’t returned to her job, choosing instead to be a full- time mother to the couple’s now 1. Sean and Amelie. A fitness fanatic, she finds comfort in daily work- outs at the gym.

Gerry Mc. Cann, 4. Leicester University as well as an internationally renowned cardiologist at Glenfield General Hospital in Leicester. Toys left by well- wishers at the War Memorial in Rothley. Madeleine’s untouched bedroom is piled high with a decade’s worth of unopened birthday and Christmas presents — a symbol of the couple’s unwavering conviction their eldest daughter could come home one day. The Mc. Canns have found different ways to cope with their daughter's disappearance. Kate finds comfort in daily work- outs at the gym, while Gerry has thrown himself into his work. He was recently praised for saving the life of former Leicester City footballer Alan Birchenall after he suffered a heart attack and ‘died’ for seven minutes.

The events of Thursday, May 3, 2. UK, Madeleine disappeared from her bed while her parents dined with friends at a nearby tapas restaurant. She was reported missing at 1. Despite being the subject of one of the biggest missing person investigations of all time, no trace of the little girl, who was about to turn four, has ever been found. While every possible theory has been investigated — that Madeleine was abducted by a paedophile or child traffickers, that she was killed during a bungled burglary or that she simply wandered out of the apartment and died in an accident — Kate and Gerry Mc.

Cann have doggedly refused to give up the search for her. A source close to the family, who still live in the same large detached house, told the Mail this week that the couple ‘have come a long way’ over the past decade.‘The Mc. Canns are incredibly strong as a family,’ said the source.

There was a time when Kate never left the house, but she has found some normality for herself.‘She goes to the gym almost every day. She is extremely fit and attends spinning and pilates classes and a running club. Exercising clearly helps her.

She looks really well, much better than she has for a long time. I am so pleased for her.’ The family, the source added, speak ‘openly and often’ of Maddie. On May 3, the Mc. Canns, who are devout Catholics, will also join supporters to pray for Madeleine’s safe return at an informal outdoor gathering in Rothley. The prayers will be led by the local Anglican vicar, the Rev Rob Gladstone, in front of the village war memorial where a candle continues to burn around the clock in her memory.

The Mc. Canns are also preparing for a one- off television interview at the end of this month to mark the anniversary of their daughter’s disappearance. Pictured: The Ocean Club apartments in Praia Da Luz, Portugal, where Madeleine Mc. Cann disappeared in May 2.

Pictured: British police officers searching an area of land in the resort in 2. The search failed to uncover any leads. It is not known if they will be joined by the friends who were with them in Portugal at the time Madeleine disappeared, but the Mc.

Canns remain close to the so- called ‘Tapas Seven’ whose lives were also transformed by the tragedy. Among the close- knit group of friends were Dr David Payne, now 5. Dr Fiona Payne, now 4. The couple flew to Praia da Luz with the Mc.

Canns from East Midlands airport in April 2. Fiona’s mother Dianne Webster, now 7.

Also among the group were Dr Russell O’Brien, now a 4. Royal Devon and Exeter Hospital and his partner, marketing consultant Jane Tanner, also 4. Madeleine. The last couple to join the Mc. Canns were Dr Matthew Oldfield, now a 4. Kingston Hospital in Surrey, and his recruitment consultant wife Rachael, 4. None of the Mc. Canns’ friends have ever spoken about the events that took place that night. In Praia da Luz, however, locals are keen to put the mystery behind them.

Leader of Praia da Luz parish council, Victor Mata, told the Mail this week that people living there wanted to ‘forget, not remember’ that night’s events and that the town was ‘deeply scarred by something that we still haven’t got answers for.’He said: ‘We’re not going to be doing anything officially to mark the anniversary. People here want to forget and put this behind them, not dwell on it.’The retired 7. Madeleine’s disappearance affected this town very badly.

What happened — a little girl vanishing in mysterious circumstances, was terrible in itself and it was compounded by the years of publicity which led to Luz’s name becoming known worldwide for all the wrong reasons. Pictured: The continued investigation has caused a backlash from locals in Praia Da Luz, with this graffiti scrawled on walls in the resort in 2. Watch The Three Stooges Online Forbes. This town depends on tourism and for four years after it happened, holidaymakers stayed away. It’s only been in the last two years or so that the tourists have been coming back in greater numbers.‘This year we’re expecting a record year that is going to be even better than the period before Madeleine disappeared.‘When I’m out on the streets here I see happy, relaxed families with smiling children from Britain and elsewhere, enjoying this beautiful place for what it is.’Around the Ocean Club, there are superficial changes. The tapas bar and restaurant where the Mc. Canns dined with their friends has been replaced with a snack bar only open at lunchtimes. Gone, too, are the childcare centres where Madeleine and the twins spent time painting and playing, although the Ocean Club does offer a ‘Kids Club’ during the summer season and a baby- sitting service charged by the hour.

Holiday company Mark Warner, which arranged the Mc. Canns’ holiday, pulled out of the resort in January 2. UK via Thomas Cook. At the heart of the resort is the now- infamous apartment 5.